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KMID : 0390320070170020142
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Chungbuk Medical Journal
2007 Volume.17 No. 2 p.142 ~ p.149
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The Effect of Remifentanil-Based Total Intravenous Anesthesia(TIVA) on the Hemodynamic Response to the Endotracheal Intubation
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Kim Sang-Tae
Park Sang-Hi
Shin Hyun-Jung
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Abstract
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Purpose: Tracheal intubation is a useful procedure in general anesthesia, but hypertension and tachycardia may happen after that. So, effects of remifentanil-based total intravenous anesthesia on the hemodynamic responses to endotracheal intubation and skin incision were investigated.
Materials and Methods: Twenty-one patients were randomly allocated into 2 groups. Each group received 2 or 4 ng/ml of remifentanil-based total intravenous anesthesia before tracheal intubation, respectively. Blood pressure(BP) and heart rate(HR) were recorded at pre-anesthesia(control), pre-intubation, pre-skin incision and during the 5 minutes after intubation and skin incision.
Results: BP and HR were similar during post-skin incision period compared to the pre-skin incision values in two groups. However HR was significantly higher during post-intubation period for 3 minutes in 2 ng/ml than 4 ng/ml of remifentanil group.
Conclusion: To reduce tachycardia incidence after tracheal intubation, 4 ng/ml is recommended rather than 2 ng/ml of remifentanil.
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KEYWORD
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Blood pressure, Hear rate, Propofol, Remifentanil, Tracheal intubation
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